Integrated Biological Markers for the Prediction of Treatment Response in Depression (Updated!)
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The Canadian Biomarker
Integration Network in Depression (CAN-BIND) is a national
program of research and learning. From 2013 to 2017, data were collected from 211
participants with major depressive disorder and 112 healthy
individuals with an average age of 35 years...
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| Version: 2.0 | Date Released: 2023-03-10 | ||
| Participants: 309 | Files: 14 990 | Size: 159.55 GB | |
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Cohorts: Major Depressive Disorder, Healthy Controls Scans: EEG (resting state), fMRI (resting state), DTI, T1W, PDT2 Tasks: Emotional Face Categorization/Conflict Task (fMRI), go/no-go task (fMRI), anhedonia task (fMRI) Timepoints: Baseline, Phase 1 (Week 2, Week 4, Week 6, Week 8), (Phase 2 coming soon) Modalities: fMRI, Structural MRI, Diffusion tensor imaging, Electroencephalography, Genomics, Metabolomics, Methylation, Inflammatory markers Formats: BVAL, BVEC, CSV, EDAT, EDF, FDT, JSON, NIfTI, SET |
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For further information
Lam RW, Milev R, Rotzinger S et al. (2016). BMC Psychiatry.
EpUp Study: A Pilot Intervention for People with Epilepsy & Depression
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About one third of people with epilepsy experience comorbid depression. UPLIFT
(Using Practice and Learning to Increase Favorable Thoughts) uses mindfulness-based
cognitive behavioural therapy (CBT) principles to treat depression in people with
epilepsy. The EpUp study aimed to examine outcomes of UPLIFT versus EpINFO, an
epilepsy information and self-management program. The effects of these
distance-delivery, group intervention programs were studied in adults with
epilepsy and self-reported depressive symptoms...
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| Version: 1.0 | Date Released: 2022-11-25 | ARK ID: 70798/d7k2604zp75tn8bkb1 | |
| Participants: 66 | Files: 240 | Size: 10.13 MB | |
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Cohorts: UpLift, EpInfo, Wait-List Control Timepoints: Pre Waitlist (T1), Pre Intervention (T1/T1a), Post Intervention (T2), Short Term Followup (T3), Long Term Followup (T4) Modalities: Clinical studies, Distance-delivery, Group intervention, Mindfulness cognitive behavior therapy, Self-management Formats: CSV |
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For further information
Do distance-delivery
group interventions improve depression in people with epilepsy?
Hum KM, Chan CJ, Gane J, Conway L, McAndrews MP & Smith ML (2019). Epilepsy & behavior.
CP-NET: Hemi-NET Clinical Database
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This controlled data release focuses on CP-NET's initial Clinical Database which solely focused
on children and youth, aged 2-18, with a confirmed diagnosis of hemiplegic
cerebral palsy (CP). The Hemi-NET Clinical Database has data on 323 children and
youth from across Ontario...
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| Version: 1.0 | Date Released: 2022-10-17 | ARK ID: 70798/d7wx86hhx5mj34339s | |
| Participants: 322 | Files: 10 | Size: 47.24 GB | |
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Conditions: Infantile cerebral palsy, hemiplegic Scans: MR-T1w, MR-T2w, MR-FLAIR, DTI, Angio, CT, MR-PDT2, MR-PDw, MRS Timepoints: Phase 1 Data - Single Time Point Modalities: CytoScan microarray, Neuroimaging, Demographics, Risk factors, Neurodevelopmental Formats: CSV, PDF, TXT |
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For further information
Fehlings D, Krishnan P, Ragguett RM, deVeber G, Gorter JW, Hunt C, Kim M, Mesterman R. McCormick A & CP-NET Group (2021). Dev Med Child Neurol.
Province of Ontario Neurodevelopmental Disorders Network (POND) Imaging Data
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The Province of Ontario
Neurodevelopmental Disorders (POND) Network is an Integrated
Discovery Program funded by the Ontario Brain Institute and aims to
understand the neurobiology of neurodevelopment disorders and translate the
findings into effective new treatments...
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| Version: 1.0 | Date Released: 2022-02-22 | ARK ID: 70798/d7qv7rj6b98w66v7m3 | |
| Participants: 2784 | Files: 15 | Size: 1.0 GB | |
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Conditions: ADHD, Autism spectrum disorder, Obsessive-compulsive disorder, Anxiety, Fragile X syndrome, 22q11.2 deletion syndrome, Tourette's syndrome Scans: MR-T1 & MR-T2 (anatomy), DTI (resting state), MRS, MRS (GABA-ACC), MEG (resting state), GRE Tasks: Emotion processing fMRI task paradigm (faces), Social cognition (theory of mind) fMRI task, Stop signal task (fMRI), Set-shifting task (MEG), Go/no-go task (MEG), Social attribution task (MEG), Inscape task (MEG) Timepoints: Single Timepoint Modalities: Genetics, Neuroimaging, MRI, MEG, Neurobiology Formats: CSV |
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For further information
Baribeau DA, Dupuis A, Paton TA, Scherer SW, Schachar RJ, Arnold PD, Szatmari P, Nicolson R, Georgiades S, Crosbie J, Brian J, Iaboni A, Lerch J & Anagnostou E (2017). Scientific reports.
Ontario Neurodegenerative Disease Research Initiative (ONDRI): Foundational Study Baseline Data - Release 1
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ONDRI's Foundational study includes data from 520
people living with Alzheimer’s Disease, Mild Cognitive Impairment,
Parkinson’s Disease, Amyotrophic Lateral Sclerosis, Frontotemporal
Dementia, or Cerebrovascular Disease, along with their care
partners...
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| Version: 1.0 | Date Released: 2022-06-08 | ARK ID: 70798/d7r439px587bx4v6vq | |
| Participants: 520 | Files: 176 | Size: 10.85 MB | |
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Conditions: Alzheimer's disease, Cognitive impairment, Parkinson's disease, Amyotrophic lateral sclerosis, Frontotemporal dementia, Unspecified cerebrovascular disease Timepoints: Baseline, Screening (additional timepoints coming soon) Modalities: Cohort study, clinical, Cognitive, Gait and balance, Eye tracking, Retinal imaging, Genetic markers, Neuroimaging, Neuropsychological assessment, Cross-disease, Cross-platform, Caregiver, Deep pheotyping Formats: CSV, TXT |
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For further information
Characteristics of the Ontario Neurodegenerative Disease Research Initiative cohort.
Sunderland KM, Beaton D, Arnott SR, Kleinstiver P, Kwan D, ,Lawrence-Dewar JM, Ramirez J, Tan B, Bartha R & Black SE (2022). Alzheimer's & Dementia.
Additional Resources
| ONDRI’s Research Initiative | ONDRI's Data Standards | Data Standards and Processes Videos |
